| Item Type | Name |
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Concept
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Acetates
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Concept
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Aerobiosis
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Concept
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Sodium-Potassium-Exchanging ATPase
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Concept
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Amino Acid Sequence
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Concept
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Base Sequence
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Concept
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Cations, Divalent
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Concept
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Eukaryotic Cells
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Concept
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Cerebellum
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Concept
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Cysteine
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Concept
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Cytoplasm
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Concept
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Chromatography, Liquid
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Concept
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Hippocampus
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Concept
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Ouabain
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Concept
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Liposomes
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Concept
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Escherichia coli
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Concept
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Fluorine Radioisotopes
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Concept
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Magnesium
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Concept
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Picrates
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Concept
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Macaca mulatta
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Concept
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Indocyanine Green
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Concept
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Molecular Sequence Data
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Concept
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Monte Carlo Method
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Concept
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Mice, Inbred C57BL
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Concept
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Motion
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Concept
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Ion Channels
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Concept
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Ligands
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Concept
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Oocytes
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Concept
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Phenylurea Compounds
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Concept
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Radioactive Tracers
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Concept
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Potassium Channels
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Concept
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Humans
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Concept
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CHO Cells
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Concept
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United States Food and Drug Administration
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Concept
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Protein Engineering
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Concept
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Calcium Channels
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Concept
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Sodium Channels
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Concept
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Locomotion
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Concept
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Water
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Concept
|
4-Aminopyridine
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Concept
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Ion Channel Gating
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Concept
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Mitochondria
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Concept
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Molecular Probes
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Concept
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Mutagenesis, Site-Directed
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Concept
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Muscle Contraction
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Concept
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Genes, Reporter
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Concept
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DNA, Complementary
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Concept
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Clione
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Concept
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Sodium-Glucose Transporter 1
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Concept
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Kv1.1 Potassium Channel
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Concept
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Kv1.3 Potassium Channel
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Concept
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Sodium Channel Blockers
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Concept
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Drosophila Proteins
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Concept
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Pertussis Toxin
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Concept
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Shaker Superfamily of Potassium Channels
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Concept
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Ether-A-Go-Go Potassium Channels
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Concept
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Amino Acid Substitution
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Concept
|
Thermotoga maritima
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Concept
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Potassium Channels, Inwardly Rectifying
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Concept
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Receptors, Nicotinic
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Concept
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RNA, Messenger
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Concept
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Spinocerebellar Degenerations
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Concept
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Swimming
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Concept
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Receptor, Muscarinic M2
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Concept
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HEK293 Cells
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Concept
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Stereoisomerism
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Concept
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Temperature
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Concept
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Large-Conductance Calcium-Activated Potassium Channel alpha Subunits
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Concept
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PTEN Phosphohydrolase
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Concept
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Hydrophobic and Hydrophilic Interactions
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Concept
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Molecular Structure
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Concept
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Cation Transport Proteins
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Concept
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History, 20th Century
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Concept
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KCNQ1 Potassium Channel
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Concept
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KCNQ2 Potassium Channel
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Concept
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Kv1.2 Potassium Channel
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Concept
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KCNQ Potassium Channels
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Concept
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Shaw Potassium Channels
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Concept
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Fluorescent Dyes
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Concept
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Immunologic Techniques
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|
Concept
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Infrared Rays
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Concept
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Lymphocytes
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Concept
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Lysine
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Concept
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Movement
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Concept
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Protons
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Concept
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DNA Primers
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Concept
|
Potassium Channels, Voltage-Gated
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Concept
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Receptor, Muscarinic M1
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Concept
|
Microscopy, Electron, Transmission
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Concept
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Large-Conductance Calcium-Activated Potassium Channels
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Concept
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Large-Conductance Calcium-Activated Potassium Channel beta Subunits
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Concept
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Intermediate-Conductance Calcium-Activated Potassium Channels
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Academic Article
|
Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation.
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Academic Article
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A physical model of potassium channel activation: from energy landscape to gating kinetics.
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Academic Article
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Structural biology. Force and voltage sensors in one structure.
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Academic Article
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Voltage sensor movements.
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Academic Article
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Coupling interactions between voltage sensors of the sodium channel as revealed by site-specific measurements.
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Academic Article
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Detecting rearrangements of shaker and NaChBac in real-time with fluorescence spectroscopy in patch-clamped mammalian cells.
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Academic Article
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Extensive editing of mRNAs for the squid delayed rectifier K+ channel regulates subunit tetramerization.
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Academic Article
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A fluorometric approach to local electric field measurements in a voltage-gated ion channel.
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Academic Article
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The voltage-sensor structure in a voltage-gated channel.
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Academic Article
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RNA editing of a human potassium channel modifies its inactivation.
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Academic Article
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Voltage-gated ion channels.
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Academic Article
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Small vertical movement of a K+ channel voltage sensor measured with luminescence energy transfer.
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Academic Article
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Gating charge displacement in voltage-gated ion channels involves limited transmembrane movement.
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Academic Article
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A proton pore in a potassium channel voltage sensor reveals a focused electric field.
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Academic Article
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Optical detection of rate-determining ion-modulated conformational changes of the ether-à-go-go K+ channel voltage sensor.
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Academic Article
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Movement of 'gating charge' is coupled to ligand binding in a G-protein-coupled receptor.
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Academic Article
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S4-based voltage sensors have three major conformations.
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Academic Article
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Fluorescence detection of the movement of single KcsA subunits reveals cooperativity.
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Academic Article
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The origin of subconductance levels in voltage-gated K+ channels.
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Academic Article
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Silicon chip-based patch-clamp electrodes integrated with PDMS microfluidics.
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Academic Article
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A single charged voltage sensor is capable of gating the Shaker K+ channel.
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Academic Article
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Gating currents from neuronal K(V)7.4 channels: general features and correlation with the ionic conductance.
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Academic Article
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How membrane proteins sense voltage.
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Academic Article
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Gating currents from Kv7 channels carrying neuronal hyperexcitability mutations in the voltage-sensing domain.
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Academic Article
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An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations.
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Academic Article
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The contribution of individual subunits to the coupling of the voltage sensor to pore opening in Shaker K channels: effect of ILT mutations in heterotetramers.
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Academic Article
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In search of a consensus model of the resting state of a voltage-sensing domain.
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Academic Article
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Twitches in the presence of ethylene glycol bis( -aminoethyl ether)-N,N'-tetracetic acid.
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Academic Article
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Distance measurements reveal a common topology of prokaryotic voltage-gated ion channels in the lipid bilayer.
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Academic Article
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The action potential: from voltage-gated conductances to molecular structures.
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Academic Article
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Ion channels: from conductance to structure.
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Academic Article
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Nano-positioning system for structural analysis of functional homomeric proteins in multiple conformations.
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Academic Article
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Molecular mechanism for depolarization-induced modulation of Kv channel closure.
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Academic Article
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Intermediate state trapping of a voltage sensor.
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Academic Article
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The voltage sensor and the gate in ion channels.
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Academic Article
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Fast gating in the Shaker K+ channel and the energy landscape of activation.
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Academic Article
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Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction.
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Academic Article
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Properties of deactivation gating currents in Shaker channels.
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Academic Article
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Control of a final gating charge transition by a hydrophobic residue in the S2 segment of a K+ channel voltage sensor.
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Academic Article
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Ouabain binding site in a functioning Na+/K+ ATPase.
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Academic Article
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IKs channels open slowly because KCNE1 accessory subunits slow the movement of S4 voltage sensors in KCNQ1 pore-forming subunits.
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Academic Article
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Thermal mechanisms of millimeter wave stimulation of excitable cells.
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Academic Article
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A structural rearrangement of the Na+/K+-ATPase traps ouabain within the external ion permeation pathway.
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Academic Article
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Native chemical ligation at Asx-Cys, Glx-Cys: chemical synthesis and high-resolution X-ray structure of ShK toxin by racemic protein crystallography.
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Academic Article
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Molecular bases for the asynchronous activation of sodium and potassium channels required for nerve impulse generation.
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Academic Article
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S3-S4 linker length modulates the relaxed state of a voltage-gated potassium channel.
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Academic Article
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Moving gating charges through the gating pore in a Kv channel voltage sensor.
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Academic Article
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Resting state of the human proton channel dimer in a lipid bilayer.
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Academic Article
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Kv3.1 uses a timely resurgent K(+) current to secure action potential repolarization.
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Academic Article
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ß1-subunit-induced structural rearrangements of the Ca2+- and voltage-activated K+ (BK) channel.
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Academic Article
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Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin.
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Academic Article
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Mechanism of functional interaction between potassium channel Kv1.3 and sodium channel NavBeta1 subunit.
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Academic Article
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Development of a PET radioligand for potassium channels to image CNS demyelination.
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Academic Article
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Replacing voltage sensor arginines with citrulline provides mechanistic insight into charge versus shape.
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Academic Article
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Charge translocation by the Na/K pump.
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Academic Article
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Determination of the Stoichiometry between a- and ?1 Subunits of the BK Channel Using LRET.
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Academic Article
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LRET Determination of Molecular Distances during pH Gating of the Mammalian Inward Rectifier Kir1.1b.
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Academic Article
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Gating currents.
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Academic Article
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Nonsensing residues in S3-S4 linker's C terminus affect the voltage sensor set point in K+ channels.
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Academic Article
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Noncanonical mechanism of voltage sensor coupling to pore revealed by tandem dimers of Shaker.
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Academic Article
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Metal Bridge in S4 Segment Supports Helix Transition in Shaker Channel.
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Academic Article
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Loss-of-function BK channel mutation causes impaired mitochondria and progressive cerebellar ataxia.
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Academic Article
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Molecular basis for functional connectivity between the voltage sensor and the selectivity filter gate in Shaker K+ channels.
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Academic Article
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Gating current noise produced by Brownian models of a voltage sensor.
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Academic Article
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Tracking the movement of discrete gating charges in a voltage-gated potassium channel.
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Academic Article
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Noncanonical electromechanical coupling paths in cardiac hERG potassium channel.
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Concept
|
Voltage-Gated Sodium Channels
|
|
Concept
|
NAV1.4 Voltage-Gated Sodium Channel
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Concept
|
In Vitro Techniques
|
|
Grant
|
ISS ChronosBH Fluorescence Lifetime Spectrometer
|